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sterol regulatory element binding protein |
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sterol regulatory element binding protein [¦ste‚rȯl ¦reg·yə·lə‚tȯr·ē ‚el·ə·mənt ′bīnd·iŋ ‚prō‚tēn]
(biochemistry) A transcription factor required for the active transcription of genes that encode the low-density lipoprotein receptor and enzymes in cholesterol synthesis. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | SREBP (sterol regulatory element-binding protein) that stimulates synthesis of fatty acids in the liver, and AMPK (adenosine mono-phosphate kinase) that turns SREBP on and off. The researchers focused on two key regulators of lipid (fat) metabolism that are found in many human cells as well: SREBP (sterol regulatory element-binding protein) that stimulates synthesis of fatty acids in the liver, and AMPK (adenosine monophosphate kinase) that turns SREBP on and off. 1038/nature06179), Alnylam scientists and collaborators demonstrated the ability of synthetic siRNAs to silence three distinct hepatocyte-expressed genes -- apolipoprotein B, factor VII, and SREBP cleavage-activating protein, or "SCAP" -- to levels of greater than 80 percent with both single dose and repeat dose administration of target-specific siRNAs in mice or hamsters. |
Srebp |
SRDIS SRDJ SRDL SRDL SRDM SRDMC SRDMG SRDN SRDO SRDP SRDR SRDRN SRDRS SRDS SRDT SRDU SRDV SRDW SRE SRE SRE1 SREA SREAW SREB SREB-CCEN Srebnoe Srebp SREBP cleavage activating proteinSREBP-1 SREBP1 SREBP2 Srebrenica Regional Recovery Programme SREC Srecko Kosovel SRECS SRED SREDA Sredi Kollektsionerov Sredinnyi Range Sredna Gora Sredna mountains Srednee Srednee Spetsialnoe Obrazovanie Srednekolymsk Sredneuralsk Sredniaia Akhtuba Srednie Veka Srednii Egorlyk Srednja Gradbena, Geodetska in Ekonomska Sola Sree Sree Sree Sree Sree Chitra Thirunal College of Engineering | |||||||
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