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streptomycin
(redirected from Streptomycin sulfate)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.
streptomycin (strĕp'tōmī`sĭn), antibiotic antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms.

Types of Antibiotics


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 produced by soil bacteria of the genus Streptomyces and active against both gram-positive and gram-negative bacteria (see Gram's stain Gram's stain, laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls.
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), including species resistant to other antibiotics, e.g., some streptococci, penicillin-resistant staphylococci, and bacteria of the genera Proteus and Pseudomonas. Originally isolated by Selman A. Waksman and Albert Schatz in 1947, streptomycin is effective against tubercle bacilli and is a mainstay of tuberculosis therapy. Because streptomycin-resistant tubercle bacilli emerge during treatment, the antibiotic is usually used in combination with one or more of the drugs isoniazid isoniazid (ī'sōnī`əzĭd), drug used to treat tuberculosis .
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, ethambutol, and aminosalicylic acid. Streptomycin acts by inhibiting protein synthesis and damaging cell membranes in susceptible microorganisms. Possible side effects include injury to the kidneys and nerve damage that can result in dizziness and deafness.

streptomycin

Antibiotic synthesized by the actinomycete Streptomyces griseus, found in soil. It was among the first antibiotics discovered (1943, by Selman Waksman), after penicillin, gramicidin, and tyrocidine. The first antibiotic effective against tuberculosis, it interferes with the tubercle bacillus's ability to synthesize certain vital proteins. It still has some use in combination with penicillin for treating endocarditis and with tetracyclines in the treatment of plague, tularemia, and brucellosis.


streptomycin
an antibiotic obtained from the bacterium Streptomyces griseus: used in the treatment of tuberculosis and Gram-negative bacterial infections. Formula: C21H39N7O12

streptomycin [‚strep·tə′mīs·ən]
(microbiology)
C21H39O12N7A water-soluble antibiotic obtained fromStreptomyces griseusthat is used principally in the treatment of tuberculosis.


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Bilateral Meniere's disease: Treatment with intramuscular titration streptomycin sulfate.
 
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