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cell fractionation |
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cell fractionation [¦sel ‚frak·shə′nā·shən] (cell and molecular biology) A laboratory technique that uses differential centrifugation to separate the different components of the cell, resulting in nuclear, mitochondrial, microsomal, and soluble fractions. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ABSTRACT The subcellular fractionation of the digestive gland cells of the common cuttlefish Sepia officinalis was performed to investigate the distribution of metals between organelles and cytosol and the different cytosolic fractions separated by gel-filtration chromatography. For example, tools for tissue or subcellular fractionation may reside squarely in the biological domain, but could also be designed in such a way as to maximize synergy with widely used analytical separations methods. Through subcellular fractionation, eight proteins never before found in tumor vasculature were identified in this study, and dozens more that can serve as unique biomarkers and therapeutic transport agents are expected to be identified, Dr. |
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