Substrate Phosphorylation

0.01 sec.

in biochemistry, the synthesis of energy-rich phosphorus compounds using the energy of the oxidation-reduction reactions of glycolysis, which are catalyzed by phosphoglyceraldehyde dehydrogenase and enolase. It also takes place upon oxidation of α-ketoglutaric acid in the Krebs cycle (under the action of a-ketoglutarate dehydrogenase and succinate thiokinase). For bacteria, cases of substrate phosphorylation upon oxidation of pyruvic acid have been described.

Substrate phosphorylation, in contrast to phosphorylation in an electron transport system (seeOXIDATIVE PHOSPHORYLATION), is not inhibited by general poisons, such as dinitrophenol, and is not related to the fixation of enzymes in mitochondrial membranes. The contribution of substrate phosphorylation to the cellular supply of adenosine triphosphate under aerobic conditions is significantly less than the contribution of phosphorylation in an electron transport system.

Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.

?Page tools

Printer friendly
Cite / link

Feedback

Mentioned in	?		References in periodicals archive	?		Encyclopedia browser	?		Full browser	?
No references found			Therefore, similar allosteric regulation of substrate phosphorylation may have a more general meaning and play a significant role in various 'decision-making' steps of the cell cycle. Single-subunit allostery in the kinetics of peptide phosphorylation ... by Kuznetsov, Aleksei; Jarv, Jaak / Proceedings of the Estonian Academy of Sciences Cellular substrate phosphorylation studies targeting the inhibition of PI3K and functional cellular assays of tumor cell proliferation have been performed. AEterna Zentaris Discloses First In Vitro Data for its PI3K ... by PR Newswire			Substantivization substation Substation, Electric-Power Substatutory Act substellar object substellar point substituent Substitute substitute mode Substitution substitution alphabet Substitution Bone substitution cipher substitution group Substitution Method Substitution of Organs substitution reaction Substitution Reactions substitution solid solution substitution weighing substitutional impurity substitutive nomenclature substrain Substrate substrate failure Substrate Phosphorylation substratosphere Substratum substring Substructure Subsurface subsurface contour subsurface course subsurface current Subsurface Flow subsurface geology Subsurface Ice subsurface investigation subsurface irrigation subsurface radar subsurface sand filter subsurface sewage disposal system subsurface tillage subsurface utility subsurface waste disposal subsurface wave subsynchronous subsynchronous resonance subsystem Subsystem for UNIX-based Applications subtangent			Substract with Carry Substraction Substraction Substractor substrain substrata substrata substrata substrate substrate substrate Substrate (linguistics) Substrate (linguistics) Substrate (linguistics) Substrate Attached Neurite Promoting Activity substrate binding site substrate binding site substrate binding site Substrate Conformal Imprint Lithography Substrate Contact substrate depletion phase substrate failure Substrate Integrated Folded Waveguide Substrate Integrated Image Guide Substrate Integrated Rectangular Waveguide Substrate Integrated Slab Waveguide Substrate Integrated Waveguide Substrate language Substrate language Substrate language Substrate Phosphorylation Substrate Positive-Negative-Positive Substrate Simulator Substrate specificity Substrate specificity Substrate specificity Substrate-level phosphorylation Substrate-level phosphorylation Substrate-level phosphorylation Substrate-Removed substrates substrates substrates substrative substrative substrative substratosphere substratosphere substratospheric substratospheric substratum substratum substratum Substratum (linguistics) Substratum (linguistics) Substratum (linguistics) Substratum Neurite Extension Factor substratums substratums substratums Substring

Encyclopedia

Free Tools:	For surfers: Free toolbar & extensions \| Word of the Day \| Help For webmasters: Free content \| Linking \| Lookup box \| Double-click lookup

Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.