The variation of different enzymatic activities like Amylase, Protease, Peroxidase, Succinate dehydrogenase
, Polyphenoloxidase and Nitrate reductase of eighteen marine macroalgae as per their class has been shown in Fig.
Activity of glycogen phosphorylase (GP) and the content of glycogen in cytosolic fraction and the activities of isocitrate dehydrogenase (ICDH) and succinate dehydrogenase
(SDH) in mitochondria liver and skeletal muscle of experimental animals Parameters CON FRU GP (A): Liver 4.
A number of previous reports have examined the activity of succinate dehydrogenase
Professor So Iwata of Imperial College London, who led the research, reported in the journal Science, ``Solving the structure of succinate dehydrogenase
opens up new leads in the quest to understand longevity and ageing.
Qualitative and Quantitative Evaluation of Succinate Dehydrogenase
7] Human genes: RET, ret proto-oncogene; VHL, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase; NF1, neurofibromin 1; SDHD, succinate dehydrogenase
complex, subunit D, integral membrane protein; TMEM127, transmembrane protein 127; MAX, MYC associated factor X.
These genes included succinate dehydrogenase
(SDHC), cytochrome c oxidase (COX5B/ COX6B), and various genes of the ATP synthase complex (ATP5G1, ATP5C1, ATP5J, ATP5B, ATP5A1, ATP50, and ATP5F1).
The test chemicals did not cause cytotoxicity at concentrations of 30 [micro]M and below, based on visual inspection of the cells, cell attachment, protein content of the wells, and the inability of the triazines to decrease the mitochondrial activity of succinate dehydrogenase
determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test (22).
Second, some tumors, especially those caused by mutations in the succinate dehydrogenase
subunit B gene [SDHB, succinate dehydrogenase
complex, subunit B, iron sulfur (Ip)], do not naturally produce large amounts of catecholamines, despite their unaffected secretion (2).
For example, oral administration of DEHP to rats induced liver mitochondrial swelling and reduced succinate dehydrogenase
(SDH) activity (34), and studies with isolated rat liver mitochondria showed that MEHP caused uncoupling of oxidative phosphorylation and inhibition of SDH activity (35).
multiple endocrine neoplasia type 2, neurofibromatosis type 1, von Hippel Lindau syndrome, or succinate dehydrogenase
mutations); a family history of PCC; an incidentally discovered adrenal mass; pressor response to anesthesia, surgery, or angiography; onset of hypertension at a young age (<20 years); idiopathic dilated cardiomyopathy; and a history of gastrointestinal stromal tumors or pulmonary chondromas.
Both types of tumors are associated with conditions that are inherited in an autosomally dominant manner, such as: multiple endocrine neoplasia type 2 (MEN2),  which is due to a mutation in the RET  (ret proto-oncogene) protooncogene; von Hippel-Lindau disease (VHL), which is due to a mutation in the VHL (von Hippel-Lindau tumor suppressor) gene; neurofibromatosis type 1 (NF1), caused by mutation in the NF1 (neurofibromin 1) gene; and mutations in succinate dehydrogenase
(SDH) subunits B, C, and D, which are encoded by the SDHB [succinate dehydrogenase
complex, subunit B, iron sulfur (Ip)], SDHC (succinate dehydrogenase
complex, subunit C, integral membrane protein, 15kDa), and SDHD (succinate dehydrogenase
complex, subunit D, integral membrane protein) genes.