Enzyme replacement therapy for Morquio A: an active recombinant N-acetylgalactosamine-6-sulfate sulfatase
produced in Escherichia coli BL21, Journal of Industrial Microbiology and Biotechnology, 37: 1193-201, 2010.
7-9] These Gram-negative bacteria produce enzymes sulfatase
and phosphatase, which increase the conversion of indoxyl sulfate into indoxyl and are, thus, important in the genesis of PUBS.
Except for urease, activities of the other six enzymes estimated (dehydrogenase, acid phosphatase, alkaline phosphatase, aryl sulfatase
, [beta]-glucosidase and FDHA) were, on average, higher in Inceptisols, followed by Entisols and Alfisols.
HCV, NASH cfDNA [28, 29] HBV, HCV, NASH miRNA  HBV, HCV, NASH miRNA-199a, miR-199b, miR-122a, miR-92, miR-222  HBV, HCV, NASH NF-kB, OxLDL [32-35] NASH IL-17 [36-47] NASH Adiponectin  NASH Sulfatase
2 [49-51] NASH Adiponectin  HBV IL-1[beta], IL-6, CXCL-8, TNF-[alpha] [53-55] HBV HBx  HCV PD-L1  HBV, HCV 8-OHdG [58,59] HCV [Fe.
0) and hydrolyzed enzymatically with 10 [micro]l of [beta]-glucuronidase with sulfatase
activity (Sigma G-0876, St.
mucogenicum is positive for aryl sulfatase
activity, acetamidase activity, Tween 80 hydrolysis, tellurite reduction and urease.
Nocardia strains Isolate site Phenotypic collected between differentiating 2001 and 2007 property (1) W7467 Respiratory isolate (2) W7811 Respiratory isolate Did not assimilate trehalose (3) W8061 Respiratory isolate No aryl sulfatase
production at 14 days (4) W9013 Respiratory isolate Did not assimilate D galactose Nocardia strains Genetic analysis collected between 2001 and 2007 (1) W7467 100% similar to other 3 strains (2) W7811 100% similar to other 3 strains (3) W8061 100% similar to other 3 strains (4) W9013 100% similar to other three strains
As per recent findings, steroid sulfatase
(STS) has emerged as a novel therapy target.
Effect of vitamin C and E on sulfated proteoglycan metabolism and sulfatase
and phosphatase activities in organ cultures of human cartilage.
Broth cultures used for this study with whole saliva indicated that all but sulfatase
and lysozyme were produced by the oral flora.
exonic point mutations in classical Morquio and mild cases.
Molecular basis of multiple sulfatase
deficiency, mucolipidosis II/III and Niemann-Pick C1 disease--lysosomal storage disorders caused by defects of non-lysosomal proteins.