Sulfatase


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Related to Sulfatase: sulfate, Steroid sulfatase

sulfatase

[′səl·fə‚tās]
(biochemistry)
Any of a group of esterases that catalyze the hydrolysis of sulfuric esters.

Sulfatase

 

(or sulfohydrolase), any one of several enzymes belonging to the class of hydrolases. Sulfatases catalyze the decomposition of sulfuric esters, with the release of a free sulfation. They are widespread in animals, plants, and microorganisms.

The known sulfatases act on various substrates. Aryl sulfatases hydrolyze aromatic sulfuric esters, glycosulfatases hydrolyze sulfuric esters of monosaccharides and disaccharides, chondrosulfatases decompose chondroitinsulfuric acid, sterol sulfatases hydrolyze steroid sulfuric esters, and cellulose sulfatases split the sulfo group from cellulose polysulfates. Aryl sulfatases have been studied in the greatest detail.

References in periodicals archive ?
7-9] These Gram-negative bacteria produce enzymes sulfatase and phosphatase, which increase the conversion of indoxyl sulfate into indoxyl and are, thus, important in the genesis of PUBS.
Except for urease, activities of the other six enzymes estimated (dehydrogenase, acid phosphatase, alkaline phosphatase, aryl sulfatase, [beta]-glucosidase and FDHA) were, on average, higher in Inceptisols, followed by Entisols and Alfisols.
HCV, NASH cfDNA [28, 29] HBV, HCV, NASH miRNA [30] HBV, HCV, NASH miRNA-199a, miR-199b, miR-122a, miR-92, miR-222 [31] HBV, HCV, NASH NF-kB, OxLDL [32-35] NASH IL-17 [36-47] NASH Adiponectin [48] NASH Sulfatase 2 [49-51] NASH Adiponectin [52] HBV IL-1[beta], IL-6, CXCL-8, TNF-[alpha] [53-55] HBV HBx [56] HCV PD-L1 [57] HBV, HCV 8-OHdG [58,59] HCV [Fe.
mucogenicum is positive for aryl sulfatase activity, acetamidase activity, Tween 80 hydrolysis, tellurite reduction and urease.
Nocardia strains Isolate site Phenotypic collected between differentiating 2001 and 2007 property (1) W7467 Respiratory isolate (2) W7811 Respiratory isolate Did not assimilate trehalose (3) W8061 Respiratory isolate No aryl sulfatase production at 14 days (4) W9013 Respiratory isolate Did not assimilate D galactose Nocardia strains Genetic analysis collected between 2001 and 2007 (1) W7467 100% similar to other 3 strains (2) W7811 100% similar to other 3 strains (3) W8061 100% similar to other 3 strains (4) W9013 100% similar to other three strains
As per recent findings, steroid sulfatase (STS) has emerged as a novel therapy target.
Effect of vitamin C and E on sulfated proteoglycan metabolism and sulfatase and phosphatase activities in organ cultures of human cartilage.
Broth cultures used for this study with whole saliva indicated that all but sulfatase and lysozyme were produced by the oral flora.
N-acetylgalactosamine-6-sulfate sulfatase exonic point mutations in classical Morquio and mild cases.
Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease--lysosomal storage disorders caused by defects of non-lysosomal proteins.