Isoprenoid ethers; backbone of complex lipids of the archaebacterium sulfolobus
Numerous bacterial genera have been identified which are able to reduce ferric iron, such as Pseudomonas, Bacillus, Bacteroides, Desulfovibrio, Sulfolobus
, Thiobacillus, Shewanella, Desulfomonas, Desulforomusa, Geobacter, and Pelobacter.
In this proposal I aim to understand the assembly and mechanism of rotation of the archaellum of the thermocacidophilic crenarchaen Sulfolobus
acidocaldarius by using biochemical, genetic and biophysical methods.
Eight contributions from an international roster of researchers address the following: how to construct mathematical models for systems biology; a review of Eschericia coli metabolism; bacterial chemotaxis; infection; human host cells and intracellular pathogens; principles of phagocytosis; the metabolism of Mycobacterium tuberculosis, and Sulfolobus
Two-dimensional IR correlation spectroscopy of mutants of the beta-glycosidase from the hyperthermophilic archaeon Sulfolobus
solfatari-cus identifies the mechanism of quaternary structure stabilization and unravels the sequence of thermal unfolding events.
a fatty acid of 10 or less carbons); thermophilic carboxylesterases have been obtained from Aeropyrum pernix, Alicyclobacillus acidocaldarius, Archaeoglobus fulgidus, Bacillus acidocaldarius, Pseudomonas aeruginosa, Sulfolobus
solfataricus, and Thermotoga maritime Lipase 3.
A further 14 papers are specialist articles discussing lateral gene transfer and the nature of the domains, nanoarchaeota, mechanisms of rearrangement and change in Sulfolobus
genomes, plasmids, possible role of integration mechanisms in genome evolution, genetic properties of Sulfolobus
acidocaldarius and relate Archaea, transcriptional regulation in Haloarchaea, translational mechanisms and protein synthesis, glycolytic pathways of Archaea, metabolism of inorganic sulfur compounds in Archaea, methylation of metalloids by methanoarchaea, and other topics.
Robert (Rob) Hatherill are working in the laboratory of Steve Yannone of Berkeley Lab's Life Sciences Division as members of a team studying the proteins and protein complexes that make it possible for the microbe Sulfolobus
solfataricus to thrive under conditions that would cripple most other forms of life.
Examination of the results for Sulfolobus
solfataricus reveals some of the complexity of archaeal genes (Figure 6).
Three genes (SS1, SS7, and SS9) from the Archaeon Sulfolobus
sulfataricus were studied to ascertain which protein they each coded for and a minor characterization of the proteins.
The team was studying the organism Sulfolobus
Scientists identified a thermostable hydrolizing enzyme, b-glycosidase, from genetically modified hyperthermophilic Archea Sulfolobus
solfataricus and Pyrococcus furiosus that grew in continuous fermentors.