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Sulfone

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sulfone [′səl‚fōn]
(organic chemistry)
R2SO2(or RSOOR) A compound formed by the oxidation of sulfides, for example, ethyl sulfone, C4H10SO2, from ethyl sulfide, C4H10S; the use of sulfones, particularly 4,4′-sulfonyldianiline (dapsone) in the treatment of leprosy leads to apparent improvement; relapses associated with sulfone-resistant strains have been encountered.

Sulfone 

any of several organosulfur compounds containing the

group bonded to two organic radicals. Sulfones are colorless and very stable crystalline substances; for example, diphenylsulfone, (C6H5)2SO2, melts at 128°C and boils at 379°C. Both aliphatic and aromatic sulfones are obtained by oxidation of organic sulfides; aromatic sulfones are also obtained by means of the Friedel-Crafts reaction.

Some substituted sulfones are used in medicine—for example, diaphenylsulfone (4,4’-diaminodiphenylsulfone) is used in the treatment of leprosy. Polyarylenesulfones are used for the production of packages for foodstuffs and electrotechnical parts.



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INTRODUCTION In recent years our group has been interested in the investigation of aromatic thermoplastic polymers containing ether, ketone, and sulfone groups (1-9).
The peak separation is >95% on common amino acids profile (up to 45 amino acids in a single run with Lithium systems), including Taurine, Ornithine, oxidized amino acids such as Cysteic acid and Methionine Sulfone, and hydroxylated amino acids such as Hydroxyproline and Hydroxylysine.
The second covers the removal of the functional group, the sulfone.
 
 
 
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