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Sulfone |
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sulfone [′səl‚fōn]
(organic chemistry) R2SO2(or RSOOR) A compound formed by the oxidation of sulfides, for example, ethyl sulfone, C4H10SO2, from ethyl sulfide, C4H10S; the use of sulfones, particularly 4,4′-sulfonyldianiline (dapsone) in the treatment of leprosy leads to apparent improvement; relapses associated with sulfone-resistant strains have been encountered. Sulfone any of several organosulfur compounds containing the
group bonded to two organic radicals. Sulfones are colorless and very stable crystalline substances; for example, diphenylsulfone, (C6H5)2SO2, melts at 128°C and boils at 379°C. Both aliphatic and aromatic sulfones are obtained by oxidation of organic sulfides; aromatic sulfones are also obtained by means of the Friedel-Crafts reaction. Some substituted sulfones are used in medicine—for example, diaphenylsulfone (4,4’-diaminodiphenylsulfone) is used in the treatment of leprosy. Polyarylenesulfones are used for the production of packages for foodstuffs and electrotechnical parts. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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