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supercoiling

   Also found in: Medical, Wikipedia 0.01 sec.
supercoiling [′sü·pər‚kȯil·iŋ]
(cell and molecular biology)
Winding of the deoxyribonucleic acid duplex on itself so that it crosses its own axis; may be in the same (positive) direction as, or opposite (negative) direction to, the turns of the double helix.
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impact of gyrA and parC mutations on quinolone resistance, doubling time, and supercoiling degree of Escherichia coli.
Serogroup a Neisseria meningitidis with reduced susceptibility to ... by Strahilevitz, Jacob; Adler, Amos; Smollan, Gillian; Temper, Violeta; Keller, Nathan; Block, Colin / Emerging Infectious Diseases
These enzymes control the degree of supercoiling and are required for undoing knots and tangles in the genetic material.
Origin of genetic information and evolution of biological species by Wahid, Pallacken Abdul / Islam & Science
Any breaks present in the DNA cause the supercoiling to relax locally, and negatively charged loops of DNA are then free to extend and migrate in the electric field toward the anode as a "comet tail.
DNA damage Associated with ultrastructural alterations in rat ... by Nigro, Marco / Environmental Health Perspectives
 
 
 
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