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synonymous substitution

   Also found in: Wikipedia 0.01 sec.
synonymous substitution [si·′nän·ə·məs ‚səb·stə′tü·shən]


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A synonymous substitution represents a silent change, a nucleotide change in a codon that does not result in an amino acid replacement.
1918 influenza: the mother of all pandemics by Morens, David M. / Emerging Infectious Diseases
Nonsynonymous base substitutions were more frequent than synonymous substitutions at almost all loci.
Silent nucleotide polymorphisms and a phylogeny for mMycobacterium ... by Drobniewski, Francis / Emerging Infectious Diseases
We assumed that the probability of synonymous substitution followed two separate binomial distributions, designated models A and B, with probabilities of "success" (i.
Genomewide pattern of synonymous nucleotide substitution in two ... by Murray, Megan / Emerging Infectious Diseases
 
 
 
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