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systemic inflammatory response syndrome

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systemic inflammatory response syndrome [si¦stem·ik in‚flam·ə‚tȯr·ē ri′späns ‚sin‚drōm]
(medicine)
The spectrum of elicited pathophysiologic changes (including blood clotting and changes in metabolism, heart rate, and respiration) resulting from excess production of inflammatory mediators (for example, histamines and leukotrienes), which orchestrate the process of inflammation through various processes.


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DX-88 is also in a Phase I/II trial for the prevention of blood loss and effects of systemic inflammatory response syndrome in patients undergoing coronary artery bypass graft surgery.
Sepsis is a systemic inflammatory response syndrome that results in the failure of the circulation to provide blood and oxygen to vital organs of the body.
 
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