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lupus erythematosus
(redirected from Systemic lupus erythematosis)

    Also found in: Medical, Wikipedia 0.01 sec.

lupus erythematosus

Either of two inflammatory autoimmune diseases, both more common in women. In the discoid type, a skin disease, red patches with grayish brown scales appear on the upper cheeks and nose (often in a butterfly pattern), scalp, lips, and/or inner cheeks. Sunlight worsens it. Antimalarial drugs may help. The second type, systemic (disseminated) lupus erythematosus (SLE), may affect any organ or structure, especially the skin (with marks like those of the discoid type), kidneys, heart, nervous system, serous (moisture-forming) membranes (e.g., in synovial joints or lining the abdomen), and lymph nodes, with acute episodes and remissions. Symptoms vary widely. Kidney and central-nervous-system involvement can be life-threatening. Treatment includes pain relief, control of inflammation, and trying to limit damage to vital organs.

lupus erythematosus [′lü·pəs ‚er·ə‚thē·mə′tō·səs]
(medicine)
An acute or subacute febrile collagen disease characterized by a butterfly-shaped rash over the cheeks and perilingual erythema.


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Alfred Steinberg and Joanne Muir-Nash of NIH, comparing the fatigue of MS with that of patients with systemic lupus erythematosis and with healthy people.
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Commonly called lupus, systemic lupus erythematosis (SLE), is an autoimmune disease in which the immune system attacks the body's own tissues and organs, including joints, kidneys, heart, lungs and brain.
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