tumor necrosis factor

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tumor necrosis factor

[¦tü·mər nə′krō·səs ‚fak·tər]
(immunology)
A monokine that induces leukocytosis, fever, weight loss, the acute-phase reaction, and necrosis of some tumors.
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34 Our results showed that the serum levels of TNFa and hs-CRP were decreased significantly in the supplemented group in comparison with the controls after severe exercise.
Susceptibility or protection phenotypes are shown with odds ratio (OR) and statistical significance (P-value) Population Gene origin SNP/Haplotype VDR India Codon 352 (TT) Codon 352 (CC) Codon 352 (TC) Malawi Codon 352 (CC) CR1 Malawi K1590E (GG) TNFA India -308A Brazil -308A Malawi -238/-308/-376/-863 IL10 Brazil -819T Brazil -3575A/-2849G/-2763C -3575T/-2849A/-2763C India -3575T/-2849G/-2763C/ -1082A/-819C/-592C5 Malawi -592/-819/-1082 IL12RB2 Japan -1035G -1023G -464G SNP/Haplotype Phenotype Reference Codon 352 (TT) Susceptibility to lepromatous 42 form, (OR = 1.
In the HCT-116 p53+/+ cell line, GA-T inhibited the TNFa induced NO production (##p < 0.
For the genes NQO1, TNFA, TLR4, and ADRB2, we selected tag single-nucleotide polymorphisms (SNPs) in the gene region, 10 kb upstream from the 5' untranslated region (UTR), and 10 kb downstream from 3' UTR.
KEY WORDS: Insulin resistance, Obesity, Inflammatory markers, IL6, TNFa.
In line with this, no association of the CD14 (-159C/T) polymorphism with TNFa production has been found (46).