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taxol

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.

taxol

Organic compound with a complex multi-ring molecule that occurs in the bark of Pacific yew trees (Taxus brevifolia). It is active against certain cancers of the lung, ovary, breast, head, and neck, disrupting cell division and interfering with separation of the nuclear chromosomes. A semisynthetic process to make it from yew needles and twigs eliminated the prospect of widespread destruction of yew forests, and total synthesis methods were later developed.


taxol [′tak‚sōl]
(pharmacology)
C47H51NO14An alkaloid derived from the Pacific yew tree (Taxus brevifolia) that is used in the treatment of ovarian and breast cancer.


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However, the same trial showed a 29 percent reduction in deaths for women who failed a prior Taxol regimen.
Now comes a thirty-two state lawsuit against Bristol Meyers-Squibb for allegedly violating federal and state antitrust laws by fraudulently securing patents for the anti-cancer drug Taxol and illegally manipulating regulatory and judicial proceedings.
This year, not only is generic drug maker IVAX gearing up to produce a generic form of Taxol in the United States, there is also talk of allowing drug imports.
 
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