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(organic chemistry)
(NH2)2CS Bitter-tasting, white crystals with a melting point of 180-182°C; soluble in cold water and alcohol; used in photography and photocopying, as a rubber accelerator, and as an antithyroid drug in treating hyperthyroidism. Also known as thiocarbamide.



(or thiocarbamide), H2NC(S)NH2, a white crystalline substance with a bitter taste. Melting point, 180°–182°C upon rapid heating (decomposes upon slow heating). Moderately soluble in water, methanol, and pyridine, and freely soluble in 50 percent aqueous pyridine.

Thiourea is obtained by isomerization of ammonium thiocyanate (a) and by the addition of hydrogen sulfide to cyanamide (b):

Hydrolysis of thiourea yields ammonia, hydrogen sulfide, and carbon dioxide. Alkylation of thiourea produces the S-alkyl derivatives of isothiourea, S-alkylisothiouric salts (I), which decompose under the action of alkalies to form mercaptans (II):

where X is a halogen and R is an alkyl.

Thiourea is used in the synthesis of various organic compounds, including pharmaceuticals, and as a growth substance. Thiourea yields inclusion compounds with branched and cyclic alkanes, but not with hydrocarbons of normal structure. This property is used for the separation of these two groups of compounds.


References in periodicals archive ?
2008) Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
Aerial application of mancozeb and urinary ethylene thiourea (ETU) concentrations among pregnant women in Costa Rica: the Infants' Environmental Health Study (ISA) Environ Health Perspect 122(12):1321-1328 (2014); doi: 10.
This has placed the sector under pressure to come up with an alternative, before thiourea, as is expected, is placed on a list limiting its use.
Saravanan, "Synthesis of soluble, curable, and thermally stable aromatic polyamides bearing thiourea and pendent 4-pyridylformylimino groups," International Journal of Polymeric Materials and Polymeric Biomaterials, vol.
This study was conducted to evaluate the potential of thiourea in improving the terminal heat resistance in bread wheat.
compound (A) is at least one compound selected from the group consisting of a polyamideimide, a poly-amide, a polyamide acid and a polyimide, wherein the anti-oxidizing material (B) is at least one compound selected from the group consisting of a polyarylene sulfide, an amine compound, a benzotriazole-based compound, a benzothiazole-based compound, a sulfenamide compound, and a thiourea compound, wherein the fluororesin (C) is a perfluororesin.
The sulfur-based crosslinking agents are sulfur, pipentamethylenethiuram tetrasulfide, zinc-N-dibenzyl-dithiocarbamate, N,N'-diphenyl thiourea, ethylene thiourea and dibenzothiazyl disulfide, sulfur silanes, sulfur siloxanes, and chlorothio sulfonamides.
Our research has focused on using thiourea derivatized polymer flocculants for the removal of inorganic phosphate in water.
So the thiourea and acid in the immersion tin baths solubilize the areas of mask that are not cross-linked, leaving a negative foot.
ii) 2-Aryl/aryloxy-thiourea-5-aryl-1,3,4-thiadiazoles: Aryl or aryloxy thiourea (0.
Spinner, E, "The Vibration Spectra and Structures of the Hydrochlorides of Urea, Thiourea and Acetamide.