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thrombosis
(redirected from Thromboembolic disease)

   Also found in: Medical, Wikipedia, Hutchinson 0.01 sec.
thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus). Arterial thrombosis is generally more serious because the supply of oxygen and nutrition to an area of the body is halted. Thrombosis of one of the arteries leading to the heart (heart attack; see infarction myocardial infarction or heart attack is usually caused by a blockage in one of the coronary arteries that supply blood to the heart muscle. The blockage typically occurs when a blood clot (see thrombosis ) lodges in an area already narrowed by arteriosclerosis ; other
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) or of the brain (stroke stroke, destruction of brain tissue as a result of intracerebral hemorrhage or infarction caused by thrombosis (clotting) or embolus (obstruction in a blood vessel caused by clotted blood or other foreign matter circulating in the bloodstream); formerly called
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) can result in death and, in a vessel of the extremities, may be followed by gangrene gangrene, local death of body tissue. Dry gangrene, the most common form, follows a disturbance of the blood supply to the tissues, e.g., in diabetes, arteriosclerosis, thrombosis, or destruction of tissue by injury.
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. Acute arterial thrombosis often results from the deposition of atherosclerotic material in the wall of an artery, which gradually narrows the channel, precipitating clot formation (see arteriosclerosis arteriosclerosis (ärtĭr'ēōsklərō`sis)
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). A thrombus that breaks off and circulates through the bloodstream is called an embolus embolus (ĕm`bələs), foreign matter circulating in and obstructing a blood vessel.
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.

thrombosis

Formation of a blood clot (thrombus) in the heart or a blood vessel. Contributing factors include injury to a blood vessel's lining from inflammation (thrombophlebitis) or atherosclerosis, blood flow that is turbulent (e.g., from an aneurysm) or sluggish (e.g., from prolonged bed rest), or coagulation abnormalities (e.g., from high numbers of platelets or excessive fats in the blood). Thrombosis, especially in deep veins of the leg, is a particular danger after major surgery. A thrombus can block blood flow at the point of clot formation or break free to block it elsewhere (embolism).


thrombosis
1. the formation or presence of a thrombus
2. Informal short for coronary thrombosis

thrombosis [thräm′bō·səs]
(medicine)
Formation of a thrombus.


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He also was to be given an anticoagulant as a preventive measure for thromboembolic disease.
Venous thromboembolic disease in users of low-estrogen combined estrogen-progestin oral contraceptives, Contraception, 2004, 70(1):3-10.
PS Walls, MD, Canada Research Chair in Thromboembolic Disease, is Professor, Department of Medicine and Clinical Epidemiology Unit, University of Ottawa and the Ottawa Health Research Institute, Ottawa, Ontario, Canada.
 
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