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thrombolytic drug

   Also found in: Medical, Wikipedia 0.03 sec.
thrombolytic drug (thrŏm'bəlĭt`ĭk) or clot-dissolving drug, substance, such as streptokinase or tissue plasminogen activator (tPA), that causes the breakdown of blood clots (see thrombosis thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus).
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) that obstruct the flow of blood through the vessels. Its uses include injection during or shortly after a heart attack or stroke stroke, destruction of brain tissue as a result of intracerebral hemorrhage or infarction caused by thrombosis (clotting) or embolus (obstruction in a blood vessel caused by clotted blood or other foreign matter circulating in the bloodstream); formerly called
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 (see infarction myocardial infarction or heart attack is usually caused by a blockage in one of the coronary arteries that supply blood to the heart muscle. The blockage typically occurs when a blood clot (see thrombosis ) lodges in an area already narrowed by arteriosclerosis ; other
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) to prevent clots from blocking blood flow to the heart muscle or brain.

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The thrombolytic drug tissue Plasminogen Activator (tPA), used for treating stroke, is only available to patients who can be treated within three hours of the onset of a stroke.
The hospital across town, like others in the nation, used thrombolytic drugs instead.
The preclinical and Phase I testing of BB-10153 showed that the drug may overcome the risk of bleeding associated with currently-prescribed thrombolytic drugs.
 
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