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thrombolytic drug |
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thrombolytic drug (thrŏm'bəlĭt`ĭk) or clot-dissolving drug, substance, such as streptokinase or tissue plasminogen activator (tPA), that causes the breakdown of blood clots (see thrombosis thrombosis (thrŏmbō`sĭs), obstruction of an artery or vein by a blood clot (thrombus). ..... Click the link for more information. ) that obstruct the flow of blood through the vessels. Its uses include injection during or shortly after a heart attack or stroke stroke, destruction of brain tissue as a result of intracerebral hemorrhage or infarction caused by thrombosis (clotting) or embolus (obstruction in a blood vessel caused by clotted blood or other foreign matter circulating in the bloodstream); formerly called ..... Click the link for more information. (see infarction myocardial infarction or heart attack is usually caused by a blockage in one of the coronary arteries that supply blood to the heart muscle. The blockage typically occurs when a blood clot (see thrombosis ) lodges in an area already narrowed by arteriosclerosis ; other ..... Click the link for more information. ) to prevent clots from blocking blood flow to the heart muscle or brain. |
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During 1985-1999 changes in treatment occurred, such as introduction of thrombolytics and increased angioplasty. In many of these initiatives, process measures such as use of thrombolytics in heart attack patients are starting to give way to results measures such as risk-adjusted mortality rates for patients undergoing bypass grafts. It remains to be seen whether the practices described in this study are reflected in larger stroke cohorts and whether such blood pressure management varies with the use of thrombolytics or in the realm of clinical trials. |
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Thrombolytics
