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thromboxane
(redirected from Thromboxanes)

   Also found in: Medical, Wikipedia 0.04 sec.
thromboxane [‚thräm′bäk‚sān]
(biochemistry)
Any member of a group of 20-carbon fatty acids related to the prostaglandins and derived mainly from arachidonic acid.


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58,63) This process leads to an increase in circulating tissue levels of various cytokines, (177-180) leukotrienes, (181) thromboxanes, (182) platelet activating factor, (183) complement components, (184) elastases, and other enzymes, (185) and it causes the formation of additional ROS.
Certain prostaglandins known as the thromboxanes are potent stimulators of platelet activity,[148] and platelet aggregation is often responsible for causing thrombosis in the coronary arteries, especially if these arteries have already been partially obstructed by atherosclerotic lesions.
From arachidonic acid the body forms a large array of hormonelike substances (prostaglandins, leukotrienes, thromboxanes, and lipoxins), which are vital in controlling and promoting the activities of every cell in the body.
 
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