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tight junction |
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tight junction [¦tīt ′jəŋk·shən] (cell and molecular biology) An intercellular junction composed of a series of fusions of the junctional membrane, forming a continuous seal; serves as a selective barrier to small molecules and as a total barrier to large molecules. Also known as impermeable junction; occluding junction; zonula occludens. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The low-magnification micrographs showed no evidence of tight junctions between the apical poles of the cells or the presence of gap junctions. If the cells that line the intestine represent bricks in a wall, tight junctions are the mortar that binds them together, or so scientists long thought. Zonulin is an endogenous signaling protein that transiently and reversibly opens the tight junctions ("tj") between the cells of epithelial and |
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