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tissue
(redirected from tissue plasminogen activator)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia, Hutchinson 0.06 sec.
tissue, in biology, aggregation of cells that are similar in form and function and the intercellular substances produced by them. The fundamental tissues in animals are epithelial, nerve, connective, and muscle tissue; blood and lymph are commonly classed separately as vascular tissue. In the higher plants, there are four main types of tissue: (1) meristematic tissue (apical meristem and cambium), composed of cells that grow, divide, and differentiate into all the other cell types; (2) protective tissue (epidermis and cork), composed of thick-walled cells that cover roots, stem, and leaves; (3) fundamental tissues, consisting of cells that make up the bulk of the plant body, including parenchyma (thin-walled cells used for food storage), collenchyma (moderately thick-walled cells used for strength), and sclerenchyma (heavily thick-walled cells used for support in stems and roots); and (4) vascular tissue (xylem and phloem), specialized cells used for conduction. Organs are usually composed of several tissues. In many diseases there are apparent changes in tissue (see pathology pathology, study of the cause of disease and the modifications in cellular function and changes in cellular structure produced in any cell, organ, or part of the body by disease.
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). Histology histology (hĭstŏl`əjē)
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 is the study of the structure of tissues.

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The thrombolytic drug tissue Plasminogen Activator (tPA), used for treating stroke, is only available to patients who can be treated within three hours of the onset of a stroke.
The two agents, which were launched in Japan in May 1991, are based on a recombinant tissue plasminogen activator developed by US firm Genentech.
Most strokes result from clots, but only about 1 in 20 patients receives the sole clot-dissolving drug approved for treating stroke, tissue plasminogen activator (tPA).
 
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