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transketolase

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
transketolase [¦tranz′kēd·ə‚lās]
(biochemistry)
An enzyme that cleaves a substrate at the position of the carbonyl carbon and transports a two-carbon fragment to an acceptor compound to form a new compound.


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Benfotiamine also activates a key enzyme called transketolase, which renders these triosephosphates harmless, thus inhibiting the damaging action of glycation.
Measuring erythrocyte thiamine transketolase before and after the addition of thiamine pyrophosphate will detect a deficiency in thiamine.
A diagnosis of thiamine deficiency can be supported by decreased levels of erythrocyte transketolase, but it's important not to wait for lab results.
 
 
 
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