Transpeptidation

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Transpeptidation

the transfer of an amino acid residue or peptide residue from one compound, usually a peptide, to another in living cells. The reaction, which may be catalyzed by such proteolytic enzymes as trypsin and chymotrypsin, proceeds without substantial changes in free energy, and the total number of peptide bonds (—CO—NH—) in the system remains unchanged. Transpeptidation is used by the cell in the biosynthesis of proteins.

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