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tumor suppressor gene |
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tumor suppressor gene [¦tüm·ər sə′pres·ər jēn] (cell and molecular biology) A class of genes which, when mutated, predispose an individual to cancer by causing the loss of function of the particular tumor suppressor protein encoded by the gene. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Both the activation of oncogenes and the inactivation of tumor suppressor proteins are involved in these pathways. Velcade is also known to prolong expression of other tumor suppressor proteins such as p53. |
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