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tyrosine hydroxylase

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tyrosine hydroxylase [‚tī·rə‚sēn hī′dräk·sə‚lās]
(biochemistry)
A specialized enzyme located only in catecholamine-containing nerve cells, where it serves as the primary regulatory or rate-limiting step in catecholamine biosynthesis.
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This allele predisposes one to increased tyrosine hydroxylase (TH) activity, and TH activity serves as a biochemical index of activity of noradrenergic neurons and the adrenal medulla.
Chinese medical pattern discrimination and genomics by Flaws, Bob / Townsend Letter
Activated forms of pyridoxine, niacin, iron, and tetrahydrobiopterin are cofactors for the enzymes tyrosine hydroxylase and tryptophan 5-hydroxylase, which participate in brain biosynthesis of catecholamines and serotonin.
Herbal, nutritional therapies can play supportive role in practice by Wendling, Patrice / Clinical Psychiatry News
They contrasted the effects on cell viability, DNA synthesis associated with cell replication, and increased expression of enzyme markers that characterize cholinergic or catecholaminergic phenotypes: choline acetyltranferase (CHAT) and tyrosine hydroxylase (TH), respectively.
A fine differentiation: chlorpyrifos and neuronal development by Josephon, Julia / Environmental Health Perspectives
 
 
 
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