peptic ulcer (redirected from Ulcus pepticum)

peptic ulcer: see ulcer.

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peptic ulcer

Sore that develops in the mucous membrane of the stomach (more frequent in women) or duodenum (accounting for 80% of ulcers and more frequent in men) when its ability to resist acid in gastric juice is reduced. It causes burning ache and hungerlike pain. Ulcers can bleed, perforate the abdominal wall, or block the gastrointestinal tract. Stress and diet were blamed until Helicobacter pylori bacteria and long-term use of aspirin and similar drugs were shown to be the two major causes. The former is treated with combination drug therapy and the latter by stopping the causative drugs if possible or with drugs that reduce acid production. A rare cause is Zollinger-Ellison syndrome, in which a tumour causes increased acid secretion. Cigarette smoking slows healing and promotes recurrence.

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peptic ulcer

Pathol an ulcer of the mucous membrane lining those parts of the alimentary tract exposed to digestive juices. It can occur in the oesophagus, the stomach, the duodenum, the jejunum, or in parts of the ileum

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peptic ulcer [′pep·tik ′əl·sər]

(medicine)

An ulcer involving the mucosa, submucosa, and muscular layer on the lower esophagus, stomach, or duodenum, due in part at least to the action of acid-pepsin gastric juice.