After 12-week treatment, it was found that, the combined treatment group had a remarkably lower incidence of urge urinary incontinence
, 24-h urination frequency and night urination frequency and significantly improved IPSS and QOL.
Group 1 included 20 women with urge urinary incontinence
, which was prescribed monotherapy with Driptan.
The primary purpose of the Refractory Urge Urinary Incontinence
and Botulinum A toxin Injection (RUBI) randomized clinical trial is to compare the effect of 200 units of intradetrusor botulinum toxin A (Botox) versus placebo on improvement in urinary symptoms in neurologically normal women with DOI refractory to at least two first-line urge incontinence treatments.
The 12-week, randomized, double-blind, placebo-controlled, parallel-group study assessed the efficacy of Toviaz 8 mg compared to Toviaz 4 mg in reducing urge urinary incontinence
in subjects with OAB after 12 weeks of treatment.
The data stratification into responders and nonresponders was helpful, as were the tables and figures that demonstrated who was helped by BFB for their urge urinary incontinence
To qualify for the study, patients had to have symptoms of OAB with symptoms of urge urinary incontinence
, urgency and frequency, and experience a minimum of three urinary urgency leakage (incontinence) episodes and at least 24 urination episodes (micturitions) over a three-day timeframe.
Among white women, the group with urge urinary incontinence
had the lowest increases in urethral closure pressure during muscle contraction, 45% lower than continent women and 43% lower than those with stress incontinence.
Combining behavioral therapy and an anticholinergic medication for urge urinary incontinence
may yield a superior result after either modality alone has been disappointing by the patient's account of success.
An antispasmodic, antimuscarinic agent for the treatment of overactive bladder with symptoms of urge urinary incontinence
, urgency, and urinary frequency.
BACKGROUND Urge urinary incontinence
has drawn attention recently, with a number of studies looking at which treatment provides the best results with the fewest side effects.
Ditropan XL provides control of overactive bladder for many patients -- treating the symptoms of urge urinary incontinence
, urgency, and frequency -- and has been demonstrated to significantly reduce the incidence of urinary accidents.
Toviaz reduced urge urinary incontinence
(UUI) in patients with OAB who had a suboptimal response (less than 50 percent reduction in UUI) to Detrol LA (tolterodine tartrate extended release), a commonly-prescribed treatment for the condition.