Under the optimum chromatographic conditions, the retention time (Tr) of four kinds of standard reference substance including uridine
, guanosine, adenosine and cordycepin, was 4.
Abbreviations used: Ala, alanine; Cr, creatine; Cho, choline; PC, phosphocholine; GPC, glycerophosphocholine; Tau, taurine; Gly, glycine; Lac, lactate; [beta]-Glc, [beta]- glucose; UDP, uridine
2'-diphosphate; NADP, nicotine adenine dinucleotide phosphate.
Abbreviations: WEL, wedelolactone; OH, hydroxyl group; UGT, uridine
diphosphate-glucuronosyltransferase; HPLC, high-performance liquid chromatography; SPE, solid-phase extraction; NMR, nuclear magnetic resonance; UPLC, ultraperformance liquid chromatography; Q-TOF MS, quadruple time-of-flight mass spectrometry; HLM, human liver microsome; HIM, human intestine microsome; HKM, human kidney microsome; UDPGA, uridine
5'-diphosphate-glucuronic acid; UV, ultraviolet; COSY, correlation spectroscopy; HSQC, heteronuclear single quantum correlation spectroscopy; HMBC, heteronuclear multibond correlation spectroscopy; ROESY, rotating frame nuclear Overhauser effect spectroscopy; IDA, information-dependent acquisition; DMSO, dimethyl sulfoxide.
The enzymic interconversion of uridine
diphosphogalactose and uridine
, a pyrimidine nucleoside, has been postulated to protect fat cells from the adverse effects of thymidine analogues.
The nutrients include omega-3 polyunsaturated fatty acids, eicosapentaenoic acid, uridine
and choline, together with phospholipids and B vitamins.
67% and was supplemented with 2% glucose, 10 mM uridine
and uracil, and 0.
monophosphate, 625 mg: Required for the formation of RNA and DNA, which are essential for proper brain function, and for signaling molecules involved in memory and other brain functions.
0] medium: complete small airway growth medium containing uridine
(50 pg/mL), sodium pyruvate (1 mM), HEPES (20 mM), and glucose (4.
Thymidine like uridine
acts as a bidentate ligand involving N(3) and O(4) in metal binding  and rules out the possibility to bind through the deoxyribose unit .
Metabolism: Febuxostat is extensively metabolized by both conjugation via uridine
diphosphate glucuronosyltransferase (UGT) enzymes and oxidation via cytochrome p450 (CYP) enzymes including and non-p450 enzymes.
Yu and Karijolich studied pseudouridine, a slightly different version of the RNA component uridine