Single-assay combination of Epstein-Barr virus (EBV) EBNA1- and viral capsid
antigen-p18-derived synthetic peptides for measuring anti-EBV immunoglobulin G (IgG) and IgA antibody levels in sera from nasopharyngeal carcinoma patients: Options for field screening.
The viral capsid
may be just a protein "crystal" with a genome inside.
Gelbart were struck by the fact that experiments dating back to the 1960s showed that viral capsids
with icosahedral symmetry will form spontaneously in a solution of capsid proteins, given the right conditions of temperature, pH, and salinity.
The 3' end of Norwalk virus mRNA contains determinants that regulate the expression and stability of the viral capsid
protein VP1: a novel function for the VP2 protein.
Instead of detecting a single specific protein associated with the invader, they detect repetitive molecules linked together, such as those found in a bacterial cell wall or viral capsid
Within the envelope, the viral capsid
is made of thousands of copies of another viral protein, p24.
Immunoglobulin A against viral capsid
antigen of Epstein-Barr virus and indirect mirror examination of the nasopharynx in the detection of asymptomatic nasopharyngeal carcinoma.
Novira Therapeutics (Delaware), developing first-in-class antiviral therapeutics based on a novel mechanism of action that targets viral capsid
In contrast, viral capsid
, the protein coat of the virus, induced inflammation similar to intact virus.
By preserving the authentic conformation of the viral capsid
, VLPs mimic the antigen presentation of the live virus while lacking the ability to reproduce or cause illness.
In a patient with acute EBV mononucleosis, the heterophile antibody test will be positive, as will tests for IgM viral capsid
antigen (VCA) and IgG VCA.
IgM antibodies against the viral capsid
of EBV were determined by indirect immunofluorescence (EBV IgM IFA Test-GULL).