The lab developed a unique set of chemical compounds, or PIR cross-linkers, that would interact with the structural proteins that guide the virion
on its journey.
The surface morphology and phase of pinostrobin-treated virions
changed in a time- and concentration-dependent manner (Figs.
Because Vif inhibits APOBEC3G, its cleavage by hammerhead ribozymes may decrease the infectivity of HIV-1 virions
Bevirimat targets the Gag structural polyprotein, the fundamental structural protein of HIV, which undergoes a series of complex interactions both with itself and with other cellular and viral factors to achieve the assembly of infectious virions
Those cases have been identified as a zoonotic disease among inhabitants of small villages in the tropical rain forests of Africa, where the transmission of the virions
occurred between the rodent reservoir, monkeys, and the human population.
Distribution of hemagglutinin and neuraminidase on influenza virions
as revealed by immunoelectron microscopy.
The protease has a slightly different shape amongst everyone, in particular, in the protein's active zone where it slices the components that forms the next virion
are nonenveloped, with icosahedral symmetry and a double capsid containing 10 double-stranded RNA segments that can be separated by polyacrylamide gel electrophoresis into 3 size classes: large (L1-L3), medium (M1-M3), and small (S1-S4) (2,3).
The eventual total number of doses available also depends on the fate of the biologics license application for Fluarix (influenza vaccine [split virion
, inactivated]), which GlaxoSmithKline submitted in late May.
The United States as represented by the Department of Health and Human Services (Washington, DC) has patented a method for inactivating a virion
of an enveloped RNA virus comprising contacting the virion
with an eosinophil-derived ribonuclease, such as eosinophil-derived neurotoxin (EDN) or eosinophil cationic protein (ECP).
London, Mar 12 (ANI): A new study from Heidelberg University Hospital has analysed the involvement of particular components of the infected cell in virion
release, and discovered that the enzyme VPS4A plays a more active role in the process than was previously thought.
Dubbed oculorespiratory syndrome (ORS), the previously unrecognized and mostly mild phenomenon was linked to one manufacturer's vaccine that contained a high level of unsplit virion