factor VIII

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factor VIII

[′fak·tər ′āt]
(biochemistry)
antihemophilic factor
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References in periodicals archive ?
It is a bleeding disorder in which deficiency of von Willebrand factor results in impaired primary hemostasis due to defective adhesion of platelets and destabilization of factor VIII protein.
FREQUENCY OF VON WILLEBRAND DISEASE IN PATIENTS OF HEAVY MENSTRUAL BLEEDING
Von Willebrand factor collagen binding (VWF:CB) activity was measured by an in-house ELISA assay using bovine Achilles tendon collagen type I for capturing (Sigma-Aldrich) and polyclonal rabbit anti-human VWF antibodies (DakoCytomation) for detecting.
Biological Variation of Hemostasis Variables in Thrombosis and Bleeding: Consequences for Performance Specifications
Cleavage of ultra-large von Willebrand factor by ADAMTS-13 under flow conditions.
Is it time for Ristocetin to step down? Comparison study between a new automated von Willebrand factor activity assay and the von Willebrand factor ristocetin activity assay
Effects of desmopressin acetate on platelet aggregation, von Willebrand factor, and blood loss after cardiac surgery with extracorporeal circulation.
Effect of Desmopressin on Platelet Aggregation and Blood Loss in Patients Undergoing Valvular Heart Surgery
Relationship between ABO blood group and von Willebrand factor levels: from biology to clinical implications.
Blood group distribution and its relationship with bleeding time and clotting time
Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis.
Use of the ADAMTS13 Activity Assay Improved the Accuracy and Efficiency of the Diagnosis and Treatment of Suspected Acquired Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopaenic purpura (TTP) is a rare multi - systemic disorder of small vessels that is associated with deficiency of the von Willebrand factor - cleaving protease ADAMTS,13 which promote platelet adhesion and aggregation, leading to multiple platelet thrombi in the microcirculation.
THROMBOTIC THROMBOCYTOPAENIC PURPURA IN A PATIENT PRESENTING WITH SICKLE CELL -HEMOGLOBIN S DISEASE VASOOCCLUSIVE CRISES AND ACUTE CHEST SYNDROME
Von Willebrand Factor (VWF) is a polymeric plasma glycoprotein comprising multiple 250-kDa subunits that facilitates platelet adhesion to the vessel wall by linking platelet membrane receptors to the subendothelium and is the cornerstone of platelet--endothelial interaction.
DDAVP might reduce the risk of Preeclampsia in pregnant women with VWF deficiency / DDAVP VWF Eksikligi olan Gebelerde Preeklampsi Riskini Azaltabilir
ADAMTS-13 is a plasma metalloprotease that cleaves von Willebrand factor (vWF).
Post-cardiac surgery thrombotic thrombocytopenic purpura with digital ischaemia
These tests include: E-selectin, asymmetric dimethyl arginine (ADMA), ICAM-1, VCAM-1, CD4OL, CRP, 11-1, TNF, IFN, MCP-1, von Willebrand factor, t-PA, PAI-1 and microalbumin.
Endothelial dysfunction: the origin of atherosclerosis
Acquired vWS-2A in AS is caused by degradation of von Willebrand factor (vWF) multimers by shear stress across the diseased valve (1).
Treatment of aortic valve stenosis and gastrointestinal bleeding by transcatheter aortic valve implantation in Heyde syndrome/Heyde sendromunda transkateter aort kapak implantasyonu ile aort stenozu ve gastrointestinal kanamanin tedavisi
Interquartile range increases in pollutant concentrations were consistently associated with statistically significant increases in fibrinogen, von Willebrand factor, heart rate, sCD62P, and SCD40L concentrations," they said.
Air pollution may be global risk factor for cardiovascular disease

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