Werner's syndrome


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Werner's syndrome

[′ver·nərz ‚sin‚drōm]
(medicine)
A complex of symptoms, thought to be inherited as an autosomal recessive, including premature senescence, dwarfism, cataracts, scleroderma-like changes of the skin, osteoporosis, and multiglandular dysfunction.
References in periodicals archive ?
DISCUSSION: Werner's syndrome is a rare autosomal recessive disorder.
A report of two cases of Werner's syndrome and review of the literature.
People with Werner's syndrome show signs of accelerated aging in their 20s, develop age-related diseases and generally die before age 50.
Identification of the roles of helicase and DNA repair in the bizarrely accelerated aging process of Werner's syndrome has obvious implications for our understanding of normal aging.
The genetic variant that causes Werner's syndrome was isolated two years ago by Prof.
Keywords: age-related disease, Cockayne's syndrome, Hutchinson-Gilford progeria, premature ageing syndromes, senescence-accelerated mouse, Werner's syndrome
Young people with Werner's syndrome acquire gray hair and diseases such as osteoporosis, cataracts, and hardening of the arteries.
Researchers plowed through 650,000 nucleotides until they found a mutant gene to blame for Werner's syndrome, which causes 40-year-olds to look like - and have the infirmities of - 80-year-olds.
The collaboration capitalizes on Darwin's earlier discovery of the Werner's Syndrome gene, the first discovered human gene which directly affects the aging process.
Although there are real-life aging disorders, such as Progeria, Agrogeria and Werner's Syndrome, the ailment Jack suffers in the movie is invented.
People with the disorder, known as Werner's syndrome, begin to grow gray hair as teen-agers.