Wilson's disease


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Related to Wilson's disease: Huntington's disease

Wilson's disease

[′wil·sənz di‚zēz]
(medicine)
A hereditary disease of ceruloplasmin formation transmitted as an autosomal recessive and characterized by decreased serum ceruloplasmin and copper values, and increased excretion of copper in the urine. Also known as hepatolenticular degeneration.
References in periodicals archive ?
But Saba did not respond too well to the regularly prescribed medicines for Wilson's disease," TOI quoted liver specialist Dr Aabha Nagral, who has been treating the teen, as saying.
Wilson's disease is a rare inherited disorder that causes excess copper to accumulate in the liver, brain and other vital organs, with the symptoms typically beginning between the ages of 12 and 23.
Wilson's disease is caused by genetic disorder in which copper accumulates in liver cells.
Wilson's disease is a rare genetic disorder that prevents the body from regulating copper and can lead to serious liver and brain damage.
The presence of KF rings and jaundice with abnormal liver function tests, including low ceruloplasmin and alkaline phosphatase, suggested the diagnosis of Wilson's disease.
Hepatitis, medication toxicity Wilson's disease, malnutrition, hemochromatosis, and autoimmune liver disease must be considered in the differential.
Cara Hearst, 20, from Belfast, had Wilson's disease, which causes liver failure, and had only hours to live when she was given Daryl's liver.
What Wilson's Disease and its Treatment Have Taught us about the Metabolism of Copper.
5) The unique involvement of the central nervous system (CNS) distinguishes aceruloplasminemia from other iron or paramagnetic element storage disorders including hemochromatosis, Hallervorden-Spatz, and Wilson's disease.
The reduced concentration of CP can be a good indicator of Wilson's Disease, where copper is deposited in the skin, liver and brain, resulting in hepatic cirrhosis and neurologic damage.