xenograft

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Related to Xenografts: Allografts, xenogeneic transplantation

xenograft

[′zēn·ə‚graft]
(immunology)
A graft performed between members of different species.
References in periodicals archive ?
Distribution, DNA damage and cytotoxic effects of etoposide in human tumor xenografts in vivo.
Broad spectrum anti-cancer activity of ARQ 197, a highly selective oral c-Met inhibitor, in multiple xenograft models: In four human tumor xenograft models in athymic mice, including breast cancer, prostate cancer, colon cancer and pancreatic cancer, oral treatment with ARQ 197 inhibited tumor growth, with no observed adverse effects.
But there is no report to show berberine inhibited SCC-4 cancer cells in vivo on a murine xenograft animal model.
Efficacy studies were performed in a disseminated model of Ewing Sarcoma and subcutaneous xenograft models of breast, colon, pancreatic, small-cell lung and non small-cell lung cancer.
OSI-930 was found to have single agent in vivo activity against tumor xenografts that may be driven by wild type c-kit or mutant c-kit.
These experiments revealed a dose-responsive radiation sensitization of the IPdR on the glioblastoma xenografts.
It specialises in in vivo pharmacology services, leveraging an extensive collection of more than 400 patient-derived xenograft (PDX) tumor models, as well as a full range of in vitro assays using both commercially available and proprietary PDX-derived cell lines.
The effect of combined MTE and gefitinib on the growth of NSCLC tumour xenografts
In 2013, we published additional comparisons of human breast cancers and xenografts (2).
5, 7) However, germ cell anomalies, possibly due to DBP-related effects on Sertoli cells, have been observed in fetal rat and mouse testes as well as samples of fetal human testis xenografts (testicular tissue implanted under the skin of mice).
The collaboration will leverage the technologies of both companies to offer new mouse cancer and leukemia models based on Crown Bioscience's GEMM platform, its new human xenografts, as well as the current PDX and CDX platforms (Cell line Derived Xenograft).