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Dryness and thickening of the conjunctiva, sometimes following chronic conjunctivitis, disease of the lacrimal apparatus, or vitamin A deficiency.



an affection of the eyes expressed in dryness of the conjunctiva and cornea. It arises as a result of disturbance of tear secretion and chiefly of trophic disturbances. One of the immediate causes of xerophthalmia is avitaminosis A; it may arise in children when there are severe gastrointestinal diseases. The most frequent causes of xerophthalmia are trachoma, pemphigus, and chemical burns of the eyes. It is manifested by a sensation of dryness and pain in the eyes and heaviness of the eyelids; the cornea becomes cloudy and may undergo irreversible cicatricial changes. Vision is decreased.

Xerophthalmia is treated by medication; good results are obtained by transplanting the excretory duct of the parotid gland to the conjunctival sac to restore moisture to the eye.

References in periodicals archive ?
Complaints of xerophthalmia and joint pain are often sufficient to suspect the diagnosis (Chang et al.
In remote areas of the world, 500,000 IU of vitamin A are delivered in one dose to prevent xerophthalmia.
Punctum plugs are convenient therapy options for the treatment of xerophthalmia encountered in triple-A syndrome.
Prevalence and severity of xerophthalmia in Southern Malawi.
The power of vitamins to do good on a massive scale was illuminated for Brubaker in the 1970s, when he learned that more than 500,000 children went blind every year due to xerophthalmia, a vitamin A deficiency.
Deficiency of antioxidants causes various diseases in poultry such as retarded growth, weakness, ruffled feather, blindness, xerophthalmia etc (Hill et al.
Some 40 million children are afflicted with xerophthalmia, an eye disease that can cause blindness, and 250 million people suffer health problems because of a lack of dietary vitamin A.
A thorough interrogation highlighted recurrent xerophthalmia and a previous episode of left hemi-paresthesia lasting no more than 24 h a year ago.
Secondary Sjogren's syndrome is also common in patients with RA with both xerophthalmia and xerostomia due to inflammatory infiltration of lacrimal and salivary glands.
23) In vitamin A deficiency, linear stunting is common, xerophthalmia can occur and visual dysfunction can be the outcome.
4) The clinical manifestation of vitamin A deficiency is xerophthalmia, a collective term for abnormalities that can range from night blindness in its mildest form to permanent blindness in its most severe form.
Absence of xerostomia and xerophthalmia excludes Sjogren's syndrome, which can present with benign lymphoepithelial hyperplasia.