a1-Acid glycoprotein: an
acute phase protein with inflammatory and immunomodulating properties.
As a well-known
acute phase protein in cardiovascular diseases, hsCRP has been confirmed to be a diagnostic factor for CAD and to be associated with coronary angiographic severity.
Acute phase proteins and other systemic responses to inflammation.
Acute phase proteins are present in the blood and increase in concentration when inflammation occurs.
In particular CRP is a useful marker for infection in elderly patients and is superior both to other
acute phase proteins and to the erythrocyte sedimentation rate [5-7].
Laparoscopic surgery causes less tissue injury than conventional procedures, so the increase in concentrations of biochemical markers of inflammation, such as IL-6 and the
acute phase proteins CRP is not as high, while drop in albumin levels are also not so low.
Baltz, "
Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein," Advances in Immunology, vol.
Caption: Figure 2: Prohepcidin and
acute phase protein levels during anti-TNF therapy.
CRP is an
acute phase protein that is produced predominantly by the hepatocytes under the influence of cytokines such as Interleukin-6 and tumor necrosis factor-alpha.
Evaluation of a commercially available apparatus for measuring the
acute phase protein serum amyloid A in horses.
Expression of Lcn2 in adipose tissue can be induced by lipopolysaccharides, suggesting Lcn2 to be an
acute phase protein [5].
(14) In addition, they trigger the hepatic "acute phase response" resulting in increased synthesis and secretion of several
acute phase proteins, including Cob binding protein (C4bBP).