Cerebral hypoxia is known to be a risk factor for neurodegenerative diseases, and it implicates many pathological disorders in brain including neuron energy depletion, excitotoxicity injury and a great number of free radicals production (1, 2).
Cerebral hypoxia will progress until it becomes irreversible and death occurs.
A medical expert said: "Strangulation starves the brain of oxygen causing
cerebral hypoxia. That leads to hypoxic euphoria which gives the dreamy high.
The official cause of death was given as
Cerebral Hypoxia caused by an unassisted breech delivery.
Consultant pathologist Dr Alun Rees gave Mr Barnard's cause of death as focal cerebral necrosis and prolonged
cerebral hypoxia.
An inquest was previously told Zoe, three, died in February from
cerebral hypoxia, which involves a reduced supply of oxygen to the brain.
GlobalData's clinical trial report, "
Cerebral Hypoxia Global Clinical Trials Review, H1, 2016" provides an overview of
Cerebral Hypoxia clinical trials scenario.
Diagnostic indications for ICP monitoring include TBI, aneurysmal subarachnoid hemorrhage (SAH), spontaneous intracerebral hemorrhage, ischemic stroke accompanied by significant cerebral edema, brain tumor, neuroinfectious processes, decompensated hydrocephalus,
cerebral hypoxia or anoxia producing edema, or Reyes syndrome (Bader & Littlejohns; Dunn, 2002).
Measurement of S-100B has been proposed as a biological marker of brain damage, e.g., head injury,
cerebral hypoxia, and stroke (2), and of malignant melanoma (3).
Increased levels of 4-HNE have been identified in many pathologic processes, including Alzheimer's disease, amyotrophic lateral sclerosis, and
cerebral hypoxia. (9-11)