Table-5: CZE analysis of Au (III) in
certified reference material (SH24).
The method was validated by the analysis of triplicate samples, reagent blank,
certified reference material DORM-2 (dogfish muscles) and standard addition method.
Certified reference materials are generally accepted as providing traceable values; the reference value is then the certified value of the CRM.
(6.) IS0 15194:2009 In vitro diagnostic medical devices--Measurement of quantities in samples of biological origin--Requirements for
certified reference materials and the content of supporting documentation.
The response was linear and parallel when high-signal serum (1.87 mg/L) and plasma (3.00 mg/L) samples and the
certified reference material (5.97 mg/L) were diluted up to 8-fold.
Effect of
certified reference material 470 (CRM 470) on national quality assurance programs for serum proteins in Europe.
The majority of routinely used CRP immunoassays were calibrated with the
Certified Reference Material ERM-DA470 (previously distributed under the code BCR-470), released in 1993.
* The new FDA guidelines stipulate that cCRP assays should be standardized to
Certified Reference Material 470, whereas the hsCRP assays, at minimum, should be traceable to
Certified Reference Material 470.