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chloramphenicol

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chloramphenicol

[‚klȯr‚am′fen·ə‚kȯl]
(microbiology)
C11H12O2N2Cl2 A colorless, crystalline, broad-spectrum antibiotic produced by Streptomyces venezuelae; industrial production is by chemical synthesis. Also known as chloromycetin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Notwithstanding the lower growth rate in minimal medium plus xylose, the growth inhibition haloes were evident for both A, baumannii and K, pneumoniae in the presence of either tetracycline or chloramphenicol. In addition, the inhibition haloes measured after 12 h remained unmodified when measured after 24, 48, or 72 h (Tables S2 and S3, included in supplementary data).
All 69 isolates were sensitive to co-trimoxazole, gentamycin and ceftriaxone, 60 isolated (86.95%) were sensitive to amoxicillin and 63 (91.30%) were sensitive to chloramphenicol (see Table below).
Although PCR was not carried out in our study, none of the MRSA strains showed resistance to linezolid, chloramphenicol, clindamycin and erythromycin together, suggesting that the gene might not be present in our clinical set up yet.
Next in order of sensitivity was Ciprofloxacin 80% (4) followed by Chloramphenicol (40%).
It has shown 90% sensitivity, against MRSA according to one local study.14 Chloramphenicol is routinely used for the management of vancomycin-resistant enterococci (VRE) infections at some institutes.14 Further clinical studies specially against MRSA and vancomycin-resistant S.
PCA and HCA Analysis of the Total FIC Indices of the Essential Oil, Geraniol, Thymol, and Chloramphenicol Combinations.
The sensitivity of drugs like ampicillin chloramphenicol and co-trimaxazole were 2.8% 12.3% and 22.6% respectively.
Louis, MO), cefoperazone (sodium salt), ciprofloxacin, piperacillin (sodium salt), gentamicin (sulfate salt) obtained from Sigma, tetracycline (hydrochloride) from USB and chloramphenicol from Fluka were used.
Chloramphenicol, piperacillin-tazobactam, ertapenem and amoxicillin-clavulanate demonstrated the highest activity against these isolates, while 11% and 18% demonstrated resistance to metronidazole and clindamycin, respectively.
The sensitivity pattern showed that the resistance rate was highest for Nalidix acid (71.5%), followed by Chloramphenicol (37.5%), Ampicillin (34.8%), Co-trimaxazole (30.7%), Augmentin (14%) and Ciprofloxacin (6%).
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