The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Cineole

(also 1,8-cineole, eucalyptole), a terpene oxide having the structural formula

Cineole is a colorless liquid with an odor similar to camphor and ether. It is soluble in alcohol and ether but only slightly soluble in water. Cineole has a melting point of 1–1.5°C, a boiling point of 176–177°C, and a density of 0.923 g/cm³ at 20°C.

Cineole is obtained from many essential oils, especially eucalyptus oil; it is isolated from these oils by distilling them and then freezing out the portion that has a boiling point between 170°C and 180°C. Cineole is used in medicine and cosmetics as a component of antiseptics, expectorants, toothpastes, and elixirs.

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References in periodicals archive

[24] The cineole has antibacterial, antifungal, insecticidal, anti-inflammatory, antiparasitic, repellent, antioxidant, and analgesic properties.

Herbo-Medicinal Formulation; Marham-e-raal: A Potent Ointment for Acute and Chronic Wounds - A Review

For example, in no-choice diet trials, food intake by pygmy rabbits begins to decline above 5% cineole, but was 3-5 times higher than that of cottontails (Shipley et al.

Understanding tradeoffs between food and predation risks in a specialist mammalian herbivore

It contains 1-4% volatile oil containing cineole, zingiberene, borneol, and resins like gingerol and shogaol.

Simultaneous estimation of four antitussive components from herbal cough syrup by HPTLC

The Antitussive Effects of Menthol, Camphor and Cineole in Conscious Guinea-pigs.

Vicks induced adverse drug reactions--rare case reports

x piperita essential oil used in the pharmaceutical industry in Europe should be within the following ranges: limonene 1.0-5.0%, cineole 3.5-14.0%, menthone 14.0-32.0%, menthofuran 1.0-9.0%, isomenthone 1.5-10.0%, menthyl acetate 2.8-10.0%, isopulegol--maximum 0.2%, menthol 30.0-55.0%, pulegone--maximum 4.0%, and carvone--maximum 1.0%.

Chemosystematic markers for the essential oils in leaves of Mentha species cultivated or growing naturally in Estonia/ Eestis kultiveeritavate ja looduslikult kasvavate Mentha liikide lehtede eeterlike olide kemosustemaatilised markerid

For example, fetal exposure to an aromatic cue (cineole) followed by ethanol intoxication results in increased postnatal grasping of a surrogate nipple aromatized with cineole (Abate et al., 2002).

Preferencia por el olor del etanol tras la interaccion social con un congenere intoxicado en ratas adolescentes expuestas a la droga in utero

Others may be adulterated for economic reasons, such as the past instances where eucalyptol (used in fragrances and cosmetics) was adulterated with cineole from camphor seeds (far cheaper but with more problematic effects).

Natural products bring new customers--and risks

For example, minor synergy between 1,8 cineole and [alpha]-pinene, and 1,8 cineole and caryophyllene epoxide, and antagonism between 1,8-cineole and camphor.

Pharmacological activity of Salvia lavandulifolia and chemical components of its essential oil. A review/Actividad farmacologica de Salvia lavandulifolia Valh y los componentes quimicos de su aceite esencial

Ada cayi yapraklarinin damitilmasi ile elde edilen ada cayi yagi; salvene, pinene, camphor, cineole, borneol, thujone, sponin, diterpene, phenolic asit, salviatanin, ursokolik asit, kafeik asit ve flavonoidleri icerir (1-3).

Convulsion in infants as a result of oral use of garden sage/Ada cayi yaginin agizdan kullanimina bagli sut cocugunda konvulziyon

There are 4 tables in this chapter which even address oils known for their 1,8 cineole content as well as those with a commercial or medicinal potential.

Medicinal Plants in Australia: Volume 2 Gums, Resins, Tannin and Essential Oils