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Croton Oil

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croton oil

[′krōt·ən ‚ȯil]
(materials)
A yellow-brown oil obtained from the seeds of the Croton tiglium; used as a purgative and as a substitute for castor oil.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Croton Oil

 

a thick brownish or yellow liquid obtained from the seeds of the purging croton (Croton tiglium). Croton oil acts as a strong cathartic and irritates the skin and mucous membranes. Even in small doses (over 20 drops), it can be fatal.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
After 14 days of DMBA application, 1% croton oil was applied on skin after one hour of palmatine administration three times a week.
Extraction optimization of Tinospora cordifolia and assessment of the anticancer activity of its alkaloid palmatine
Ear edema induced by topical croton oil: Three groups of six mice were used.
Anti-inflammatory activity of Urera baccifera (Urticaceae) in Sprague-Dawley rats
Mice were anesthetized with ether and 20 [micro]l of an acetone solution containing 0.4 [micro]g croton oil and appropriate amounts of test samples were applied to the inner surface of the right ear of each mouse.
Bioactivity-guided fractionation for anti-inflammatory and analgesic properties and constituents of Xanthium strumarium L
Inflammatory response was induced on the inner surface of the right ear (surface: about 1 [cm.sup.2]) by application of 80 [micro]g of Croton oil dissolved in an appropriate vehicle, as reported below.
Anti-inflammatory activity of Maytenus senegalensis root extracts and of maytenoic acid
Croton oil, indomethacin and ursolic and oleanolic acids were Sigma products (Sigma, Milan, Italy).
Extracts and constituents of Lavandula multifida with topical anti-inflammatory activity
Hanks balanced salt solution (HBSS), croton oil, arachidonic acid, dextran, carrageenan, zymosan, plate-let-activating factor (PAF), indomethacin, phenylbutazone, methysergide, dexamethasone, phorbol-12-mirystate-13-acetate (PMA), N-formyl-methionyl-leucyl-phenylalanine (FMLP), sodium nitroprusside (SNP), W-13, H-7, genistein and propidium iodide were purchased from Sigma Chemical Co (USA).
Activity of taraxasteryl acetate on inflammation and heat shock protein synthesis
In Group I, 93.75% of animals treated with DMBA and croton oil developed skin papillomas, and the average number of tumors per mouse (tumor burden) was 6.53.98.
Chemomodulatory efficacy of Basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis
Croton oil and indomethacin were Sigma products (St Louis, USA).
Topical anti-inflammatory activity of Bauhinia tarapotensis leaves
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