supercoiling
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supercoiling
[′sü·pər‚kȯil·iŋ] (cell and molecular biology)
Winding of the deoxyribonucleic acid duplex on itself so that it crosses its own axis; may be in the same (positive) direction as, or opposite (negative) direction to, the turns of the double helix.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
The Writhing of circular cross-section rods to
DNA supercoiled .
To understand more completely how
DNA supercoils and the forces that make the strands writhe, Tamar Schlick, a mathematician and Howard Hughes Medical Institute researcher at New York University, and her colleagues have developed a computer model that links knot theory to biochemistry
Comet assay, also known as single cell gel electrophoresis (SCGE), is based on a principle that when the sperm DNA breaks,
DNA supercoils become loose and the negative charges are exposed.
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