A recent study explored the photomodulated dimerizing protein domains known as pdDronpa [71], a green fluorescent protein which
dimerizes in the dark but dissociates to monomers upon illumination with light at 500 nm [72].
When a cytokine binds to a receptor in the JAK-STAT pathway, the receptor
dimerizes and JAKs are activated.
Calcium-sensing receptor
dimerizes in the endoplasmic reticulum: biochemical and biophysical characterization of CASR mutants retained intracellularly.
As in any one-dimensional structure with a half-filled electronic band, these stacked radicals are prone to a charge density wave or Peierls instability, i.e., a tendency to
dimerize.
Activated STATs
dimerize and translocate into the nucleus binding to the promoter of target genes and activating their transcription.
The Zwitterion can
dimerize to form diperoxide (4) or give a higher peroxide (5).
The starlet sea anemone Nematostella vectensis has at least two [alpha] integrin subunits and four [beta] integrin subunits available to
dimerize and bind to the extracellular matrix or mediate sperm-egg interactions.
Gilis, "Modelling and bioinformatics analysis of the dimeric structure of house dust mite allergens from families 5 and 21: der f 5 could
dimerize as der p 5," Journal of Biomolecular Structure and Dynamics, vol.
Upon accumulation in the cytoplasm to a critical level, the proteins of PER and CRY
dimerize and translocate into the nucleus to repress the transcriptional activity of BMAL1:CLOCK/NPAS2 complex, thereby shutting down their own transcription.
In addition to its critical role in regulating ER stress-mediated apoptosis, CHOP10 may
dimerize with C/EBP[beta] and C/EBP[alpha] to serve as a transcriptional inhibitor in the regulation of adipogenesis (Ron and Habener 1992).