The title of her presentation was "Vaccination with DerG LEAPS peptide conjugates incorporating distinct PG (aggrecan)
epitopes protects by different immune mechanisms in the PG G1 domain induced mouse model of rheumatoid arthritis."
Diagnostic performance and T-cell
epitopes may be different in cattle compared to humans; it is therefore necessary to identify and verify these promising T-cell
epitopes in individuals.
Combining the results of four programs, six antigenic
epitope peptides (amino acid positions 34-45, 63-67, 103-108, 224-230, 308-316, and 365-377) were predicted (Table 3, Figures 1 and 2).
IL-7-Induced
Epitope Masking of Surface [gamma]c Protein.
Furthermore, there can be significant differences in optimal protocols required by different antibodies (eg,
epitope retrieval methods).
As neprilysin degrades
epitopes recognized by standard immunoassays for BNP, recovery of the peptide decreases.
Epitope prediction and vaccine candidate characterization have been reported first time for Pakistani field isolate of AAV-4 and could eventually be proposed as an important component of immunodiagnostics and subunit vaccine for future studies.
IgE recognizes conformational
epitopes of larger peptides (B cell
epitopes) and proteins while T cell receptors recognize small linear peptides of 8 to 10 amino acids (T cell
epitope).
An amino acid stretch must be of a minimum length for being considered as an
epitope that we are aiming to design.