Fascia adherens--(FA), desmosomal--(D), and
gap junctions (nexus) (N) are situated in the intercalated disc.
In order to study the formation of functional
gap junctions, we used the microinjection of Lucifer yellow (LY), a fluorescent dye which diffuses among cells through GJs [30].
Bedner et al., "Characterization of panglial
gap junction networks in the thalamus, neocortex, and hippocampus reveals a unique population of glial cells," Cerebral Cortex, vol.
Transient white matter lesions in X-linked Charcot-Marie-Tooth disease type 1 with novel I20T mutation of
gap junction protein beta 1 gene (in Chinese).
Global modulation mediated by
gap junctions. It has been shown that retinal
gap junctions (40,41) contribute to the neural noise reduction that is mediated by signal transmission far beyond each classical RF.
ECM-receptor interaction and
gap junction pathway were the predicted highest correlation.
For these reasons, all anti-apoptotic treatment modalities such as a Ca-sensitiserinotropic agent levosimendan, caspase and/or Poly (ADP-ribose) polymerase (PARP) inhibition, inhibition of Bax using antisense technology, adenine nucleotide transporter (ANT) antibodies,
gap junction and microtubule inhibitors in the treatment of myocardial ischaemia/ reperfusion injury can individually exert beneficial therapeutic effects.
Global Markets Direct's, 'Connexin (
Gap Junction Protein) - Pipeline Review, H1 2016', provides in depth analysis on Connexin (
Gap Junction Protein) targeted pipeline therapeutics.
Fluorescence recovery after photobleaching (FRAP) is a noninvasive technique that allows quantitative measurement of
gap junction function in living cells.
In a past study, the concentrations of metaloproteinase-3 in the supernatant of cultured synovia from patients with RA were decreased by adding a
gap junction blocker (heptanol).