The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Granulocytes

(granular leukocytes), white blood cells with specific granularity in their cytoplasm.

In invertebrate animals granulocytes are called granular amoebocytes. Granuloctyes are subdivided, according to the ability of their granules to be stained, into eosinophils (oxyphils), basophils, and neutrophils. Some vertebrate animals have functionally equivalent cells with oxyphilic granulation (pseudoeosinophils) instead of neutrophils. Granulocytes constitute the major portion of leukocytes in the blood of man. The percentage relationship between the various types of leukocytes changes with age, physiological condition, and the presence of illness. The nuclei of granulocytes are polymorphous; in neutrophils and eosinophils they are segmented. The granules of neutrophils and basophils are structureless; those of eosinophils contain unique “crystals.” It has been established that the neutrophilic granules are lysosomes, which contain hydrolytic enzymes. Granulocytes are capable of amoeboid movement and of phagocytosis. They are able to penetrate connective tissue (diapedesis) from the blood vessels and participate in inflammatory processes. Granulocytes are formed in special, hematopoietic organs.

E. S. KIRPICHNIKOVA

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References in periodicals archive

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study.

Advanced clinical parameters: achieving efficiency with automated immature granulocyte count

The characteristics included sex, age, location of the pancreas cancer, the TNM stage, outcomes, and the blood test--white blood cell (WBC), granulocyte, neutrophil, lymphocyte, and platelet--results at the time of diagnosis.

White Blood Cell and Granulocyte Counts Are Independent Predictive Factors for Prognosis of Advanced Pancreatic Caner

Patients with ATD-induced agranulocytosis were diagnosed with a granulocyte count below 0.5 x [10.sup.9]/L after taking ATDs and recovered from agranulocytosis after the cessation of ATDs.

Association of HLA-[B.sup.*]38:02 with Antithyroid Drug-Induced Agranulocytosis in Kinh Vietnamese Patients

A role for G-CSF (granulocyte colony stimulating factor) in the central nervous system.

Granulocyte colony-stimulating factor potential use in the treatment of children with cerebral palsy

DEGs in agranulocyte adhesion and diapedesis, granulocyte adhesion and diapedesis, IL-10 signaling, and IL-6 signaling were further analyzed and illustrated by the Venn diagram.

Transcriptional Profiling at High Temporal Resolution Reveals Robust Immune/Inflammatory Responses during Rat Sciatic Nerve Recovery

Level of phagocytosis (in granulocytes or monocytes) was measured by flow cytometry (FACSCalibur).

Administration of Rhodiola kirilowii Extracts during Mouse Pregnancy and Lactation Stimulates Innate but Not Adaptive Immunity of the Offspring

Wright staining results showed that granulocytes (R3) with the small nucleus and plenty of cytoplasm were the most complex and usually oval or spherical in shape and larger than hyalinocytes.

Endoenzymes and mitochondrial membrane potential associated with hemocyte types in Macrobrachium rosenbergii

Granulocytes were isolated from whole blood using a commercial kit for positive selection (StemCell Technologies Inc.), containing a tetrameric antibody complex that recognizes both the CD66b antigen and the dextran of iron-coated nanoparticles.

Diagnosis and monitoring of cystinosis using immunomagnetically purified granulocytes

Effects of BRO on leukocytes and granulocytes in peripheral blood

Bronchipret[R] syrup containing thyme and ivy extracts suppresses bronchoalveolar inflammation and goblet cell hyperplasia in experimental bronchoalveolitis