My patient was a case of
IgA nephropathy, RPRF course, extensive crescents with >50% global sclerosis.
Is
IgA nephropathy the commonest primary glomerulopathy among young adults in the USA?
IgA nephropathy which usually presents as a primary glomerular disorder characterized by episodic hematuria shows deposition of IgA in the mesangium is also known to occur in association with celiac disease due to the presence of high levels of IgA antibodies against the food antigen, gliadin in these patients [5].
Our patient had acute kidney injury and newly identified, biopsy-proven
IgA nephropathy as previously reported in patients with
IgA nephropathy who developed acute kidney injury while being treated with dabigatran.
Is presence of ANCA in crescentic
IgA nephropathy a coincidence or novel clinical entity?
Similar to patients with idiopathic
IgA nephropathy, recent studies on the glycosylation of serum IgA in patients with hepatic glomerulosclerosis identified abnormalities in the IgA hinge lesion (increase in galactosylation, decrease in sialylation), which indicates that abnormal glycosylation in the IgA hinge lesion may result in glomerular IgA deposition [3].
Sharma, "Tear of the retinal pigment epithelium and serous retinal detachment in a case of
IgA nephropathy after renal transplantation," JAMA Ophtalmology, vol.
A biopsy of the left kidney was performed at the 6th day of hospital stay and confirmed a diagnosis of
IgA nephropathy (immunofluorescence was strongly positive for mesangial IgA deposition, complement component C3, and lambda light chains and moderately positive for IgM).
Mar 16, 2015: Anthera Pharmaceuticals Announces Completion of Interim Analysis from Phase 3 Trial with Blisibimod for
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