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infantile cortical hyperostosis

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infantile cortical hyperostosis

[′in·fən‚tīl ′kȯrd·ə·kəl ‚hī·pə‚rä′stō·səs]
(medicine)
A condition occurring during the first 3 months of life in which there is fever and painful swelling of the soft tissue of the lower jaw, characterized by periosteal proliferation of the mandible.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
A novel COL1A1 mutation in infantile cortical hyperostosis (Caffey disease) expands the spectrum of collagen-related disorders.
The clinical and histopathological traits of the syndrome resemble those of canine craniomandibular osteopathy (Alexander, 1983; Gulanber et al., 2001; Huchkowsky, 2002) and human infantile cortical hyperostosis (Kamoun-Goldrat and Le Merrer, 2008).
Possible roles of Prostoglandin E1 and E2 have been suggested in some studies, in which elevated levels of serum prostaglandin E was detected in some children with infantile cortical hyperostosis, which is a similar disease to that found in humans in terms of clinical and histopathological aspects.
Infantile cortical hyperostosis, Caffey's disease, involving two cousins.
Infantile cortical hyperostosis (ICH), or Caffey's disease, has a low prevalence, is not easily recognized clinically, and is seldom reported in the primary care literature.
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