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Kinetoplast

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kinetoplast

[kə′ned·ə‚plast]
(cell and molecular biology)
A genetically autonomous, membrane-bound organelle associated with the basal body at the base of flagella in certain flagellates, such as the trypanosomes. Also known as parabasal body.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Kinetoplast

 

a cell organelle; the basal nodule of the cilia of infusoria.

The origin of the kinetoplast is associated with the centriole, an assumption supported by the similarity in ultrastructure of the two organelles. In addition to proteins, carbohydrates, and lipids, the kinetoplast contains DNA and RNA and is capable of the independent biosynthesis of protein and of self-reproduction. Kinetoplasts may give rise to cilia or trichocysts. The tendency to call all basal bodies kinetoplasts is incorrect.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
First detection of Leishmania major in peridomestic Phlebotomus papatasi from Isfahan province, Iran: comparison of nested PCR of nuclear ITS ribosomal DNA and semi-nested PCR of minicircle kinetoplast DNA.
Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran
Nuclear and kinetoplast DNA were stained with DAPI and shown by blue fluorescence.
Recombinant Enolase of Trypanosoma cruzi as a Novel Vaccine Candidate against Chagas Disease in a Mouse Model of Acute Infection
Ray, "Localization of a type II DNA topoisomerase to two sites at the periphery of the kinetoplast DNA of Crithidia fasciculata," Cell, vol.
Physiological Roles of DNA Double-Strand Breaks
Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis.
In-Vitro Antileishmanial Activity of Raphanus sativus L. var. caudatus
The present study was designed to report the prevalenceof Trypanosoma brucei in blood samples of donkeys (n=283) collected from Dera Ghazi Khan District in Punjab (Pakistan) through PCR amplification of their maxicircle kinetoplast DNA (kDNA) during four seasons in 2013 and to demonstrate the effect of this parasite on complete blood count (CBC) and selected parameters of serum.
Molecular Detection and Seasonal Prevalence of Trypanosoma brucei and its Effect on Hematobiochemical Parameters in Donkeys from Dera Ghazi Khan District in Southern Punjab, Pakistan
(4,18-22) The target DNAs for these studies have been kinetoplast DNA, rDNA (internal transcribed spacer [ITS]), repetitive nuclear DNA, mini-exon genes, and microsatellite DNA.
Inter- and intraspecific variations of Leishmania strains isolated from patients with cutaneous and visceral leishmaniases in Fars province, South of Iran
In addition, ultrastructural analyses showed remarkable alterations in the morphology of the Golgi complex, kinetoplast, endoplasmic reticulum and plasma membrane of trypomastigotes, confirming a pattern consistent with necrotic cell death.
In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi
and Trypanosoma cruzi, and is characterized by the presence of a kinetoplast (Shapiro and Englund, 1995).
Number and regulation of protozoan aquaporins reflect environmental complexity
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