linalool

[lə′näl·ə‚wȯl]

(organic chemistry)

(CH₃)₂C:CH(CH₂)₂CCH₃OHCH:CH₂ A terpene that is a colorless liquid, has a bergamot odor, boils at 195-196°C, and is found in many essential oils, particularly bergamot and rosewood; used as a flavoring agent and in perfumes. Also known as coriandrol.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Linalool

2,6-dimethyl-2,7-octadiene-6-ol, a terpene alcohol:

(CH₃)₂CCHCH₂CH₂C(CH₃) (OH) CHCH₂

A colorless liquid with a lavender odor. Boiling point, 198°-200°C; density, 0.862–0.865 g/cm³ at 20°C. Linalool exists in two optically active (+) and (-) forms, as well as the (±) form (a racemic mixture). It is readily converted into geraniol upon action of organic acids and into a mixture of terpineols in the presence of sulfuric acid. Linalool oxidizes to form citral.

Linalool is part of many essential oils (for example, coriandrol) in free form and as esters of acetic acid (linalyl acetate) and butyric acid; the rectification process is used to extract linalool from essential oils. Linalool may also be synthesized from acetylene and isoprene, as well as from α-pinene. Linalool and linalyl acetate are widely used as odoriferous substances in perfume and cosmetics manufacture.

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References in periodicals archive

Interestingly, the hybrid tambacu (Piaractus mesopotamicus males x tambaqui females) only reached deep anesthesia with EOLA-L (47.66% linalool) at a concentration of 75 [micro]L/L in approximately 5.5 min, however time to induce deep anesthesia was a little longer than 1 min at 200 [micro]L/L (SENA et al., 2016).

Anesthetic potential of the essential oils of Lippia alba and Lippia origanoides in Tambaqui juveniles/Potencial anestesico do oleo essencial de Lippia Alba e Lippia origanoides em juvenis de Tambaqui

Carson and Riley (1995) and Peana and Moretti, 2002 have demonstrated that Linalool is effective against Candida albicans, Escherichia coli, and Staphylococcus aureus, but not against Pseudomonas aeruginosa.

Herbo-Medicinal Formulation; Marham-e-raal: A Potent Ointment for Acute and Chronic Wounds - A Review

In EO studies of coriander, Beyzi and Gurbuz (2014) reported that linalool was the major component (78.94 to 85.66%) and essential oil components were I3-terpinene and camphor in CS, respectively.

PHYTOCHEMICAL COMPOSITION OF CORIANDRUM SATIVUM L. (CORIANDER) SEEDS AND ANTIBACTERIAL EFFECTS ON LAYING HENS

Standardization of "Lavaflam" tablets was performed based on the following parameters: appearance, geometric size, average weight, disintegration, abrasion resistance, compressive strength, assay (the amount of flavonoids was calculated in recalculation in isosalipurposide, lavender oil - in linalool and linalool acetate).

Development of the Composition and Manufacturing Technology of a New Combined Drug: Lavaflam/Yeni Kombine Bir Ilacin, Lavaflam, Bilesimi ve Uretim Teknolojisinin Gelistirilmesi

Thymol, linalool, and citronellol were obtained, along with technical product information (Table 1), from Quinari[R], which produces and sells essential oils and derivatives on an industrial scale.

Susceptibility of cariogenic microorganisms to phytoconstituents/Susceptibilidade de microrganismos cariogenicos a fitoconstituintes

In a study, linalool (60.72%) was characterized as the major compound in the essential oil of Mentha piperita L.

Safety Assessment of Mentha mozaffarianii Essential Oil: Acute and Repeated Toxicity Studies

However, major active component of coriander seeds was linalool, whilst, coriander leaves possess more phenolic compounds as compared to seeds.

In vitro Antioxidant and Chromatographic Quantification of Supercritical Fluid Extracts Obtained from Coriander (Coriandrum sativum L.)

Linalool and 4-terpineol are terpenoid alcohols of the monoterpene class.

Chemical Characterization and Antimicrobial Activity of Essential Oils of Mint (Mentha spicata L.) and Surinam Cherry (Eugenia uniflora L.)

Moreover, according to a number of experts, linalool is a competitive N-methyl-D-aspartate (NMDA) receptor antagonist and the blockage of glutamate NMDA receptor contributes to its antiepileptic properties.

The effect of hydroalcoholic extract of Mentha piperita on pentylenetetrazol-induced convulsion in mice

verum Component HD MWHD [gamma]-Terpinene 3.20 (5.336) Linalool 2.12 (5.856) 2.13 (5.856) Cinnamaldehyde 67.97 (8.259) 89.25 (8.568) Thymol 3.39 (8.855) 3.40 (8.859) Carvacrol Eugenol 2.73 (9.842) Caryophyllene 1.46 (11.281) % relative abundance ([t.sub.R], min) T.

Design of an Emulgel-Type Cosmetic with Antioxidant Activity Using Active Essential Oil Microcapsules of Thyme (Thymus vulgaris L.), Cinnamon (Cinnamomum verum J.), and Clove (Eugenia caryophyllata T.)

By the end of the fermentation of Criollo cacao (3 days), predominant amounts of volatiles with floral, fruity, and woody aromas including linalool, epoxylinalool, benzeneethanol, pentanol acetate, germacrene, a-copaene, aromadendrene, 3,6-heptanedione, butanal, 1-phenyl ethenone, 2-nonanone, and 2-pentanone were detected.

Another monoterpenoid that deserves attention is linalool, as recent studies have suggested a potential anesthetic activity in fish (3,10).

Monoterpenoids (thymol, carvacrol and S-(+)-linalool) with anesthetic activity in silver catfish (Rhamdia quelen): evaluation of acetylcholinesterase and GABAergic activity